Doodle Hex has been created specifically for the DS format and uses the touch screen in an intelligent spell system. The players, called ‘Doodlers’, enroll in a somewhat special Rune College, where they are taught with the intricate rune system and its use within elemental magic. Anyway, the boredom created by these classes is usually interrupted by the ghost of the school, Kalamazoo, who organizes fighting between students as a way to prove their knowledge in the art of throwing runes.

In this way, Doodle Hex takes the form of a competitive magic combat game, where players use the DS stylus to draw runes in the center of the screen, invoking spells that will transform, damage and weaken their opponent. The objective of the game is to end the energy of your opponent before he does the same with yours.