On Piso Zero the player gets into the role of Mac, a hero who must rescue the hostages of 15 buildings that are now under the control of the evil brothers Calawarr and his army.

To rescue them, the player must find each and every one of them in the different phases, and take them outside the building, avoiding the enemies. In each zone the player must rescue a different number of hostages. To do so, the hero has limited time but unlimited ammunition.